Introduction

From the depths of human history to the present day, an epic journey has been shaped by an unceasing search for transformation and renewal. The discovery of fire, the agricultural revolution, the invention of writing, the industrial age — each great leap forward demonstrated our species’ resolve to transcend its own limits. Now this journey has reached a critical crossroads: Should the future be carried forward by our biological bodies, or should the intelligence we have created take the helm? This question is not merely an existential dilemma; it draws a complex tension line between biological existence and information-processing capacity. So what truly defines us — the bodies we inhabit, the thoughts we produce, or the fabric woven by the two? This article aims to offer a broad historical and technological perspective on this fundamental question that will shape humanity’s future.

The Limits of Biological Humans — Why Evolution Falls Short

As biological beings, humans face serious challenges, particularly in long-duration space travel and interplanetary life scenarios. From the perspective of evolutionary biology, the human body was shaped by conditions Earth provided — a specific gravitational pull, a specific atmospheric pressure, a specific level of radiation. Space, an environment that meets none of these parameters, brutally exposes the fragility of our biological form. Cells defenseless against radiation, muscle and bone tissue weakening in zero gravity, lengthy recovery processes, and the psychological strain of isolation — all of these reveal how unprepared our biological form is for the demands of the space age.

NASA’s Twins Study, completed in 2019, laid out this reality with concrete data. The genomic changes Scott Kelly experienced during his year aboard the International Space Station laid bare the profound effects of long-duration spaceflight on human physiology. Findings ranging from telomere shortening to immune system degradation, muscle loss, and fluctuations in cognitive performance documented just how vulnerable our biological bodies remain under extraterrestrial conditions.

Yet the problem is not limited to space. Our survival capacity against Earth-scale threats — climate crisis, pandemics, nuclear risks — is also being seriously questioned. Evolution operates on a timescale of millions of years; yet today’s threats emerge within decades or even shorter periods. This mismatch in speed makes the question of whether biology is evolutionarily sufficient unavoidable. Perhaps evolution carried our species this far, but the same toolkit may not suffice against tomorrow’s challenges.

The Rise of Artificial Intelligence — Which Intelligence, Which Continues?

There is an opposing force we cannot ignore when discussing the limits of the human brain: artificial intelligence. In recent years, these systems have shown developments that surpass human cognitive capacity in specific domains — even rewriting how we define that capacity itself. AlphaFold solving the protein folding problem in 2020, deep learning models exceeding human-level image classification, large language models demonstrating performance on complex reasoning tasks — all of these suggest that intelligence is no longer solely a biological attribute.

These developments have moved artificial general intelligence (AGI) scenarios from speculative future predictions to a…